The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. Get rested, set and ready for anything when you stay at our Comfort Inn and Suites hotel in Santee, SC. We are close to Lake Marion, Santee Wildlife Refuge, Palmetto Trail and Santee Welcome Center. Each guest can enjoy our free breakfast, free WiFi, exercise room, seasonal outdoor pool and laundry facility. Unwind in one of our guest rooms, all of which feature a flat-screen TV, coffee maker and hair dryer. Sign up today for our Choice Privileges program and start earning rewards points with your next stay. *Some amenities may require an additional cost.
Santee
33.48477, -80.47481 Open in Google Maps
Bed room
DBL.2Q-NM
2 guests
Bed room
SUI.H6-7
6 guests
Bed room
SUI.2Q-NM
2 guests
Bed room
QUA.H6-7
4 guests
SUI
SUI.NM
8 guests
Bed room
SUI.KG-4
2 guests
Bed room
SUI.NM-5
4 guests
ROO
ROO.ST
10 guests
SUI
SUI.H6-KG
8 guests
Bed room
DBL.H6-7
2 guests
SUI
SUI.KG-1
8 guests
DBL
DBL.H6-KG
4 guests
SUI
SUI.H6-2Q
8 guests
SUI
SUI.QN
8 guests
DBL
DBL.KG
4 guests
SUI
SUI.2Q
8 guests
SUI
SUI.QN-1
8 guests
Bed room
SUI.H6-3
2 guests
Bed room
SUI.KG-5
2 guests
DBL
DBL.H6-2Q
4 guests
DBL
DBL.2Q
4 guests
SUI
SUI.ST
8 guests
Bed room
DBL.KG-NM
2 guests
DBL
DBL.NM
4 guests